Differential signal transduction of alternatively spliced FGFR2 variants expressed in human mammary epithelial cells
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چکیده
منابع مشابه
Differential signal transduction of alternatively spliced FGFR2 variants expressed in human mammary epithelial cells.
Gene amplification and protein overexpression of fibroblast growth factor receptor 2 (FGFR2) characterize the SUM-52 breast cancer cell line developed in our laboratory. SUM-52 cells express nine distinct alternatively spliced isoforms of FGFR2. Among these isoforms are two otherwise identical FGFR2 variants that express either the C1 or C3 carboxyl terminus. FGFR2-C3 variants are not normally ...
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ژورنال
عنوان ژورنال: Journal of Cellular Physiology
سال: 2006
ISSN: 0021-9541,1097-4652
DOI: 10.1002/jcp.20880